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VC가 선택한 제약바이오 | 카리스바이오 투자유치

카리스바이오(Karis Bio)가 시리즈A 단계 투자를 유치했다. 규모는 100억여원이다. 카리스바이오는 작년에 설립된 심혈관질환 세포치료제 개발업체다. 투자자로는 산업은행, 아주IB투자, 프리미어파트너스, 서울투자파트너스, 데브시스터즈벤처스 등이다.

카리스바이오, 시리즈A 103억. “내년 iPSC-EC 임상”

심혈관질환 세포치료제 개발이라는 새로운 접근법을 보여주는 카리스바이가 시리즈 A로 103억원의 투자유치를 했다고 지난 7월 밝혔다. 이번 투자금은 내년 상반기 하지말초혈관질환(POAD) 환자를 대상으로 임상시작을 계획하고 있는 인간유도만능줄기세포 내피세포(iPSC-EC) 임상개발에 투입될 예정이다.

Long-lasting blood vessel repair via stem cells

A team led by Young-sup Yoon, MD, PhD developed a new method for generating endothelial cells, which make up the lining of blood vessels, from human induced pluripotent stem cells. When endothelial cells are surrounded by a supportive gel and implanted into mice with damaged blood vessels, they become part of the animals’ blood vessels, surviving for more than 10 months.

Learn about our regenerative medicine program

Researchers in Emory University School of Medicine’s regenerative medicine program are working to develop new therapies for cardiovascular disease. Emory Department of Medicine Vice Chair and Cardiology Division Director W. Robert Taylor, MD, PhD; Rebecca Levit, MD; and Young-sup Yoon, MD, PhD discuss the program in this short video.

CV cell therapy: bridge between nurse and building block

In the field of cell therapy for cardiovascular diseases, researchers see two main ways that the cells can provide benefits: *As building blocks actually replacing dead cells in damaged tissues *As nurses — supplying growth factors and other supportive signals, but not becoming part of damaged tissues Tension between these two roles arises partly from the source of the cells.

Cardiac cell therapy: three papers at a glance

Cardiac cell therapy sounds like a promising idea: use the patients' own cells to enhance healing or even regenerate the damaged heart muscle. Doctors have taken up the promise, testing it in clinical trials involving thousands of patients. But a basic problem facing the field is this: naked cells don't appear to stay in the heart or stay alive for long enough to provide a sustained benefit.