HomeAbout Karis BioLeadershipYoung-sup Yoon, MD, PhD

CHIEF EXECUTIVE OFFICERYoung-sup Yoon, MD, PhD

Emory University School of Medicine
  • Professor of Medicine and Biomedical Engineering
  • Bruce R. Logue Chair
  • Director of Stem Cell Biology
Yonsei University College of Medicine
  • Distinguished Professor
ysyoon@karisbio.com

Career in numbers

22

YEARS OF EXPERIENCE

88

RESEARCH PUBLICATIONS

>30

AWARDS

RESEARCHAbout Dr. Yoon

The goal of his research is to develop a strategy for regenerating cardiovascular diseases using stem cells and tissue engineering technologies. Dr. Yoon has focused on generating stem cells including induced pluripotent stem cells, multipotent bone marrow cells, and directly reprogrammed cells, and developing various methods to differentiate these cells into endothelial cells.

He investigates their therapeutic utility in cardiovascular diseases such as peripheral vascular disease including diabetic complications, myocardial infarction, lymphedema and diabetic neuropathy. Mechanistically, the research focuses on angiogenesis, vasculogenesis, lymphangiogenesis and cardiomyogenesis. Recently, his research is extended into bioengineering of stem cells, reprogramming of somatic cells into target cells and restoring the function of damaged stem or progenitor cells by epigenetic modifications.

Young-Sup Yoon, MD, PhD
CEO

ACHIEVEMENTSBiography

He has made an advance toward having a long-lasting “repair caulk” for blood vessels. His research could form the basis of a treatment for peripheral artery disease, derived from a patient’s own cells.

Educations
  • Yonsei University School of Medicine, MD, 1989
  • Yonsei University School of Medicine, PhD, 1998
  • Yonsei University School of Medicine, Cardiology Fellow, 1999
  • Tufts University School of Medicine at Caritas St. Elizabeth’s Medical Center, Post-doctoral Fellow, 2002
Positions and Employment
  • Internship and Residency, Internal Medicine, Yonsei Univ. Medical Center, Seoul, Korea, 1989–1994
  • Military Service, 1994-1997
  • Fellowship, Cardiology, Yonsei University Medical Center, Seoul, Korea, 1998-1999
  • Faculty, Cardiology, Yonsei University Medical Center, Seoul, Korea, 1999-2000
  • Postdoctoral Fellowship, Caritas St. Elizabeth’s Medical Center (CSEMC), Boston, MA, 2000-2002
  • Assistant Professor, Tufts University School of Medicine, CSEMC, Boston, MA, 2003-2007
  • Director of Stem Cell Biology at CSEMC, 2006-2007
  • Associate Professor of Medicine, Tufts University School of Medicine, 2007-2008
  • Director of Stem Cell Biology, Associate Professor, Emory University, 2008-2013
  • Director of Stem Cell Biology, Professor, Emory University; Professor of Biomedical Engineering, Georgia Institute of Technology and Emory University, 2013-current
  • Distinguished Professor, Yonsei University College of Medicine, 2015-current
  • Bruce R. Logue Chair, Emory University, 2018-current
  • Member, American Heart Association Council, American College of Cardiology, International Society of Stem Cell Research, New York Academy of Science
  • Elected to Fellow of the American Heart Association, 2012
  • Elected to American Society for Clinical Investigation, 2014
Editorial Boards/Reviewer
  • Reviewer of > 30 journals including Nature Med, Lancet, J Clin Invest, Circulation, Blood, 2005 – current
  • Peer review committee, Vascular Wall Biology group and Regenerative Cardiac Biology group, American Heart Association, 2005 – current
  • Peer review committee, Ad-Hoc member, ZRG1-CVS D, Ischemic Heart Disease, NIH, 2006
  • Peer review committee, ZRG-CVS, Vascular Biology, NIH, 2006 – current
  • Ad hoc member, ZRG CVS-P, Lymphatic Biology in Health and Disease and more than 30 different study sections, 2008 – current
  • Editorial board member for Regenerative Medicine, Current Stem Cell Research and Therapy, 2005 – current
  • Editorial board member for Circulation Research, 2009 – current
  • Editorial board member for PLOS One, 2011 – current
  • Chartered member for NIH CDD (Cardiac development and differentiation) study section, 2013 – current
  • Vice chair for AHA study section (regenerative cell biology), 2015 – current
  • Editorial board member for Scientific Report, 2017 – current
  • Vice Chair, AHA BCVS council, Scientific & Clinical Education Lifelong Learning Committee, 2019 – current
Awards and Honors
  • Highest Honors Graduate in Medical School, Yonsei University, Seoul, Korea, 1989
  • Best Resident of the Year, Internal Medicine. Yonsei University Medical Center (YUMC), 1994
  • Best Fellow of the Year, Cardiology, YUMC, 1998
  • American Heart Association, New England Affiliate, Postdoctoral Fellowship Award, 2000
  • Young Investigator Award, Japanese Society of Circulation (2000, April), Osaka, Japan, 2000
  • Young Investigator Award, Society for Vascular Medicine and Biology (2002, May), Boston, USA, 2002
  • Scientist Development Grant, American Heart Association, National Center, 2003
  • Earl. Charlton Fund Research Award for new faculty, Tufts University School of Medicine, 2003
  • Melvin Marcus Young Investigator Award, Finalist, American Heart Association (2003, Nov., Orlando)
  • Young Investigator Award, Finalist, American College of Cardiology (2004 March, New Orleans)
  • Invited speaker, Intl’ Society of Heart Research; CRT; SBR (session chair); Seoul International Stem Cell Symposium (session chair); NEBS meeting, Southeast Stem Cell Symposium (keynote), 2004 – 2007
  • Session Moderator, American Heart Association, Orlando, FL, 2007 – 2009
  • American Heart Association Abstract Grader, and Invited speaker, Gordon Research Conference speaker (Lymphatic biology), 2008
  • Hilton Head workshop on stem cell biology and regenerative medicine, Co-chair, Gordon Research Conference presenter (Endothelial cell biology), TERMIS 2009 keynote speaker, 2009
  • American Heart Association Abstract Grader, 2009-current
  • Superior editorial consultant award for the journal Circulation Research; Plenary lecture at British Heart
    Foundation Summer School in Vascular Biology; Plenary lecture, Annual Conference for Baltimore Life Science Association, 2010
  • Superior editorial consultant award for the journal Circulation Research; Outstanding Research, 2011
  • Accomplishment Award, Emory University; Landmark lecture, 2011
  • The 13th South China International Congress of Cardiology, Guangzhou, China; Symposium speaker, 2011
  • 73th American Diabetic Association Annual Scientific Session, San Diego, 2011
  • Symposium speaker, European Association for Study of Diabetes, Berlin, Germany; Plenary lecture, 2012
  • Korean Diagnostic and Laboratory Medicine, Seoul, Korea; Invited speaker, 2012
  • International Symposium in Reprogramming and Stem Cells, UNIST, Korea, 2012
  • Evening symposium organizer and speaker, American Heart Association (AHA), Los Angeles, CA, 2012
  • Innovation of 2012 Award, Emory University, 2013
  • Invited speaker for Trans-NIH Angiogenesis Workshop, Bethesda, 2013
  • Invited speaker for UKC 2013, New Jersey, 2013
  • Plenary speaker, 11th Japan-Korea Joint Symposium on Vascular Biology, Jeju Island, 2013
  • Superior editorial consultant award for Circulation Research, 2013
  • Landmark lecture, The 16th South China International Congress of Cardiology, Guangzhou, China, 2014
  • Elected member, American Society for Clinical Investigation; Invited speaker for UKC 2014
  • Plenary lecture, 10th International Catholic Stem Cell Symposium, 2014
  • Session chair and invited speaker, American Heart Association, 2014
  • Faculty Excellence in Emory University School of Medicine, 2014
  • Invited Speaker, GRU Regenerative Medicine Symposium, Midwest Conference on Cell Therapy and Regenerative Medicine, Kansas City, MO; Symposium Speaker, 6th Frontier Workshop by KAST, LA, 2015
  • Invited Speaker for UKC 2014, Atlanta, GA, 2015
  • Plenary Lecture for Korean Circulation Society-Basic Research Study, Korea, 2015
  • Invited Lecture, BMES 2015, Tampa, LF, 2015
  • Symposium Organizer and Chair, United States-Korea Conference (UKC), Dallas, Texas, 2016
  • NIH Progenitor Cell Biology Consortium Cardiovascular Tissue Engineering (CVET) Symposium, Birmingham, AL, 2016
  • Chair and Symposium Speaker, 5th Gwangju-Boston Joint Cardiology Symposium, May, 2016
  • Symposium Speaker, Vascular Society and Medicine Annual Symposium, 2016
  • Symposium Organizer and Chair, United States-Korea Conference (UKC), Washington DC, 2017
  • Organizer, Yonsei Stem Cell and Cardiovascular Regeneration Symposium, Seoul, Korea, 2017
  • NIH Progenitor Cell Biology Consortium Cardiac Workshop, April, Stanford, CA, 2017
  • Invited Speaker, Gordon Research Conference, Biomaterials and Tissue Engineering, Holderness, NH, 2017
  • Invited Speaker, Midwest Conference on Cell Therapy and Regenerative Medicine, Kansas City, KS, 2017
  • Invited Speaker, American Heart Association, Irvine, CA, 2017
  • Organizer, Gwangju-Boston Cardiology Symposium, Gwangju, Korea, 2018
  • Symposium Organizer and Chair, United States-Korea Conference (UKC), New York, 2018
  • Session Chair and/or invited speaker, Korean Stem Society, American Heart Association, BMES, etc., 2018
  • Invited Speaker, International Society for Heart Research; Seminar Speakers at UNC, UAB, UGA, etc, 2019

ADVANCED-DEGREE SCIENTISTSOur Team

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CHIEF TECNOLOGY OFFICERShin-Jeong Lee, PhD

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HEAD OF CLINICAL DEVELOPMENTSong Kim, MD

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R&D DIRECTORSangsung Kim, MS